Bone Sarcoid

Bone involvement by sarcoid most commonly involves the extremities. Dr. Suwan gave me this interesting case.

A 32 yr old African American female with history of breast cancer and pulmonary sarcoidosis. Staging work-up included a bone scan.

Bone scan images showing multiple foci of increased radioactivity in the skull.
Given the history of breast cancer, the lesions were called metastasis.

CT Shows osteolytic lesions in the skull, thought to be metastasis.


Contrast enhanced MR images demonstrating multiple enhancing skull lesions.


These skull lesions were stable on 6 months follow up CT and bone scan. A direct biopsy was performed revealing non-caseating granulomas consistent with sarcoidosis. No evidence of metastasis.

Thank you, Dr. Suwan

Here is a concise link from the Univ of Washington about bone sarcoid you may find helpful. http://uwmsk.org/residentprojects/sarcoid.html